Vaccines are a great way to prevent disease. Hopefully you're up to date on all the big ones, but when was the last time you had a tetanus shot? And there has been a lot in the news lately about the HPV vaccine which can help prevent some cancers. Some drug stores are even offering shingles vaccines now.
If you aren't sure about vaccines go to your doctor and find out what you need. Most of the time this is covered under your insurance, especially for private health insurance plans. If it is going to be paid for anyway, or at reduced cost, why not get it done, it could save you a lot of hassle and pain later.